mitotic spindles in a sand dollar (Dendraster excentricus) blastocyst
history lesson time:

Even with extremely crude microscopes…Flemming and the early cell biologists deduced the correct structure of the mitotic spindle by the end of the 19th century. They even provided evidence for its filamentous properties and a force acting to parallel to the spindle axis.
In 1952, Daniel Mazia and Katsuma Dan isolated entire mitotic apparatuses, showing that the mitotic spindle, chromosomes, centrosomes, and asters constitute an integrated complex separable from the rest of the cell.

 confocal with fluorescent antibody against tubulin
credit: George von Dassow (Cell Picture Show)

mitotic spindles in a sand dollar (Dendraster excentricus) blastocyst

history lesson time:

Even with extremely crude microscopes…Flemming and the early cell biologists deduced the correct structure of the mitotic spindle by the end of the 19th century. They even provided evidence for its filamentous properties and a force acting to parallel to the spindle axis.

In 1952, Daniel Mazia and Katsuma Dan isolated entire mitotic apparatuses, showing that the mitotic spindle, chromosomes, centrosomes, and asters constitute an integrated complex separable from the rest of the cell.


confocal with fluorescent antibody against tubulin

credit: George von Dassow (Cell Picture Show)

mitotic spindles in a sand dollar (Dendraster excentricus) blastocyst
history lesson time:

Even with extremely crude microscopes…Flemming and the early cell biologists deduced the correct structure of the mitotic spindle by the end of the 19th century. They even provided evidence for its filamentous properties and a force acting to parallel to the spindle axis.
In 1952, Daniel Mazia and Katsuma Dan isolated entire mitotic apparatuses, showing that the mitotic spindle, chromosomes, centrosomes, and asters constitute an integrated complex separable from the rest of the cell.

 confocal with fluorescent antibody against tubulin
credit: George von Dassow (Cell Picture Show)

mitotic spindles in a sand dollar (Dendraster excentricus) blastocyst

history lesson time:

Even with extremely crude microscopes…Flemming and the early cell biologists deduced the correct structure of the mitotic spindle by the end of the 19th century. They even provided evidence for its filamentous properties and a force acting to parallel to the spindle axis.

In 1952, Daniel Mazia and Katsuma Dan isolated entire mitotic apparatuses, showing that the mitotic spindle, chromosomes, centrosomes, and asters constitute an integrated complex separable from the rest of the cell.


confocal with fluorescent antibody against tubulin

credit: George von Dassow (Cell Picture Show)

Notes:

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(because pluripotency is overrated)